免疫原
Synthesized peptide derived from part region of human protein AA range: 21-70
特异性
FAM3B Polyclonal Antibody detects endogenous levels of protein.
来源
Polyclonal, Rabbit,IgG
组成(Formulation)
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
稀释比例
WB 1:500-2000 ELISA 1:5000-20000
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
背景(Background)
function:Has delayed effects on beta-cell function, inhibiting basal insulin secretion from a beta-cell line in a dose-dependent manner.,miscellaneous:2 N-termini have been observed in the mature protein: the first at Glu-30, resulting from signal peptide cleavage, the second at Ser-46.,similarity:Belongs to the FAM3 family.,subcellular location:Localized in discrete vesicular and perinuclear structure.,tissue specificity:Highly expressed in the pancreas. Also found in the colon, kidney, prostate, small intestine and testis.,
功能
function:Has delayed effects on beta-cell function, inhibiting basal insulin secretion from a beta-cell line in a dose-dependent manner.,miscellaneous:2 N-termini have been observed in the mature protein: the first at Glu-30, resulting from signal peptide cleavage, the second at Ser-46.,similarity:Belongs to the FAM3 family.,subcellular location:Localized in discrete vesicular and perinuclear structure.,tissue specificity:Highly expressed in the pancreas. Also found in the colon, kidney, prostate, small intestine and testis.,
基因名称(Gene Name)
FAM3B C21orf11 C21orf76 PRED44 UNQ320/PRO365
蛋白名称
Protein FAM3B (Cytokine-like protein 2-21) (Pancreatic-derived factor) (PANDER)
细胞定位
Secreted. Present in insulin secretory granules and likely cosecreted with insulin. Localized in discrete vesicular and perinuclear structure.
组织表达
Highly expressed in the pancreas. Also found in the colon, kidney, prostate, small intestine and testis.