免疫原
Synthesized peptide derived from part region of human protein
特异性
PDCD5 Polyclonal Antibody detects endogenous levels of protein.
来源
Polyclonal, Rabbit,IgG
组成(Formulation)
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
稀释比例
WB 1:500-2000 ELISA 1:5000-20000
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
背景(Background)
This gene encodes a protein that is upregulated during apoptosis where it translocates rapidly from the cytoplasm to the nucleus. The encoded protein may be an important regulator of K(lysine) acetyltransferase 5 (a protein involved in transcription, DNA damage response and cell cycle control) by inhibiting its proteasome-dependent degradation. Pseudogenes have been identified on chromosomes 5 and 12 [provided by RefSeq, Dec 2010],
功能
developmental stage:Expression in fetal tissues is significantly lower than in adult tissues.,function:May function in the process of apoptosis.,induction:Activated in cells undergoing apoptosis.,similarity:Belongs to the PDCD5 family.,tissue specificity:Widely expressed. Highest levels in heart, testis, kidney, pituitary gland, adrenal gland and placenta.,
基因名称(Gene Name)
PDCD5 TFAR19
蛋白名称
Programmed cell death protein 5 (TF-1 cell apoptosis-related protein 19) (Protein TFAR19)
细胞定位
nucleus,cytoplasm,cytosol,extracellular exosome,
组织表达
Widely expressed. Highest levels in heart, testis, kidney, pituitary gland, adrenal gland and placenta.