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ROAA Polyclonal Antibody

说明书

BYab-06557

  • 20UL ¥460 50UL ¥945 100UL ¥1350
  • 货期: 3天左右

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宿主
反应性
应用
WB;ELISA
分子量(DA)
36kD
免疫原
Synthesized peptide derived from part region of human protein
特异性
ROAA Polyclonal Antibody detects endogenous levels of protein.
来源
Polyclonal, Rabbit,IgG
组成(Formulation)
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
稀释比例
WB 1:500-2000 ELISA 1:5000-20000
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
浓度
1 mg/ml
背景(Background)
This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are produced by RNA polymerase II and are components of the heterogeneous nuclear RNA (hnRNA) complexes. They are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene, which binds to one of the components of the multiprotein editosome complex, has two repeats of quasi-RRM (RNA recognition motif) domains that bind to RNAs. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008],
功能
function:Binds single-stranded RNA. Has a high affinity for G-rich and U-rich regions of hnRNA. Also binds to APOB mRNA transcripts around the RNA editing site.,PTM:Dimethylation at Arg-322 is probably asymmetric.,similarity:Contains 2 RRM (RNA recognition motif) domains.,subunit:Interacts with APOBEC1.,tissue specificity:Ubiquitous.,
基因名称(Gene Name)
HNRNPAB ABBP1 HNRPAB
蛋白名称
Heterogeneous nuclear ribonucleoprotein A/B (hnRNP A/B) (APOBEC1-binding protein 1) (ABBP-1)
简称
ROAA
其他名称
Fields
人基因ID
3182
人蛋白质序列数据库
Q99729
小鼠基因ID
小鼠蛋白质序列数据库
Q99020
大鼠基因ID
大鼠蛋白质序列数据库
细胞定位
Nucleus . Cytoplasm . Localized in cytoplasmic mRNP granules containing untranslated mRNAs.
组织表达
Ubiquitous.
储存(Storage)
-20°C/1 year

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ROAA Polyclonal Antibody

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