免疫原
The antiserum was produced against synthesized peptide derived from the C-terminal region of human FGF5. AA range:211-260
特异性
FGF-5 Polyclonal Antibody detects endogenous levels of FGF-5 protein.
来源
Polyclonal, Rabbit,IgG
组成（Formulation）
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
WB: 1/500 - 1/2000. IHC-p: 1:100-300 ELISA: 1/20000.. IF 1:50-200
纯化工艺（Immunogen）
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
背景（Background）
The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This gene was identified as an oncogene, which confers transforming potential when transfected into mammalian cells. Targeted disruption of the homolog of this gene in mouse resulted in the phenotype of abnormally long hair, which suggested a function as an inhibitor of hair elongation. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008],
功能
developmental stage:Can transform NIH 3T3 cells.,function:Functions as an inhibitor of hair elongation by promoting progression from anagen, the growth phase of the hair follicle, into catagen the apoptosis-induced regression phase.,similarity:Belongs to the heparin-binding growth factors family.,tissue specificity:Expressed in neonatal brain.,
蛋白名称
Fibroblast growth factor 5
其他名称
FGF5; Fibroblast growth factor 5; FGF-5; Heparin-binding growth factor 5; HBGF-5; Smag-82
Fields
>>MAPK signaling pathway;>>Ras signaling pathway;>>Rap1 signaling pathway;>>Calcium signaling pathway;>>PI3K-Akt signaling pathway;>>Regulation of actin cytoskeleton;>>Pathways in cancer;>>Chemical carcinogenesis - receptor activation;>>Melanoma;>>Breast cancer;>>Gastric cancer
组织表达
Expressed in neonatal brain.
联系我们
关注我们
您当前的位置： 
说明书
成功添加到购物车
