免疫原
Synthesized peptide derived from human protein . at AA range: 10-90
特异性
DUX5 Polyclonal Antibody detects endogenous levels of protein.
来源
Polyclonal, Rabbit,IgG
组成（Formulation）
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
稀释比例
WB 1:500-2000 ELISA 1:5000-20000
纯化工艺（Immunogen）
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
背景（Background）
double homeobox 5(DUX5) Homo sapiens The human genome contains hundreds of repeats of the 3.3-kb family in regions associated with heterochromatin. The DUX gene family, including DUX5, resides within these 3.3-kb repeated elements (Beckers et al., 2001 [PubMed 11245978]). See DUX4 (MIM 606009).[supplied by OMIM, Mar 2008],
功能
developmental stage:Expressed in fetal tissue.,domain:Homebox domain 2 confers nuclear targeting.,function:Probable transcription activator. Binds the P5 DNA element sequence 5'-GATCTGAGTCTAATTGAGAATTACTGTAC-3'.,miscellaneous:DUX genes are present in 3.3-kilobase elements, a tandem repeat family scattered in the genome found on the short arms of all acrocentric chromosomes as well as on several other chromosomes.,miscellaneous:DUX genes are present in 3.3-kilobase elements, a tandem repeat family scattered in the genome found on the short arms of all acrocentric chromosomes as well as on several other chromosomes. May be functional despite lack of introns and a poly(A) addition signal.,similarity:Belongs to the paired homeobox family.,similarity:Contains 2 homeobox DNA-binding domains.,subcellular location:Actively transported through the nuclear pore complex (NPC).,tissue specificity:Ex
蛋白名称
Double homeobox protein 5
组织表达
Expressed in hepatoma Hep3B cells.
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