免疫原
Synthesized peptide derived from part region of human protein
特异性
SYT8 Polyclonal Antibody detects endogenous levels of protein.
来源
Polyclonal, Rabbit,IgG
组成(Formulation)
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
稀释比例
WB 1:500-2000 ELISA 1:5000-20000
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
背景(Background)
This gene encodes a member of the synaptotagmin protein family. Synaptotagmins are membrane proteins that are important in neurotransmission and hormone secretion, both of which involve regulated exocytosis. Expression of the encoded protein in human pancreatic islets has been connected to activity of the promoter for the insulin gene, on the same chromosome several hundred kilobases away (PMID: 21336277 and 22928559). This association would link response to gluclose to insulin secretion. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Mar 2014],
功能
function:Not known. As it is truncated compared to orthologs, its function is not obvious.,sequence caution:The sequence differs from that shown because it is a pre-mRNA.,similarity:Belongs to the synaptotagmin family.,
蛋白名称
Synaptotagmin-8 (Synaptotagmin VIII) (SytVIII)
细胞定位
Cell membrane ; Single-pass type III membrane protein . Cytoplasmic vesicle, secretory vesicle, acrosome .
组织表达
Lung,Placenta,Testis,