免疫原
Synthesized peptide derived from part region of human protein
特异性
S12A2 Polyclonal Antibody detects endogenous levels of protein.
来源
Polyclonal, Rabbit,IgG
组成（Formulation）
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
稀释比例
WB 1:500-2000 ELISA 1:5000-20000
纯化工艺（Immunogen）
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
背景（Background）
The protein encoded by this gene mediates sodium and chloride transport and reabsorption. The encoded protein is a membrane protein and is important in maintaining proper ionic balance and cell volume. This protein is phosphorylated in response to DNA damage. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jan 2012],
功能
function:Electrically silent transporter system. Mediates sodium and chloride reabsorption. Plays a vital role in the regulation of ionic balance and cell volume.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the SLC12A transporter family.,tissue specificity:Expressed in many tissues.,
基因名称（Gene Name）
SLC12A2 NKCC1
蛋白名称
Solute carrier family 12 member 2 (Basolateral Na-K-Cl symporter) (Bumetanide-sensitive sodium-(potassium)-chloride cotransporter 1)
Fields
>>Salivary secretion;>>Pancreatic secretion;>>Vibrio cholerae infection
细胞定位
Basolateral cell membrane ; Multi-pass membrane protein .
组织表达
Expressed in many tissues.
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