免疫原
Synthesized peptide derived from human protein . at AA range: 30-110
特异性
RHOJ Polyclonal Antibody detects endogenous levels of protein.
来源
Polyclonal, Rabbit,IgG
组成(Formulation)
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
稀释比例
WB 1:500-2000 ELISA 1:5000-20000
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
背景(Background)
This gene encodes one of the many small GTP-binding proteins in the Rho family shown to be associated with focal adhesions in endothelial cells (PMID: 21148427, 22103495). The encoded protein is activated by vascular endothelial growth factor and may regulate angiogenesis. [provided by RefSeq, Dec 2011],
功能
function:GTP-binding protein with GTPase activity. Elicits the formation of F-actin-rich structures in fibroblasts and is involved in the regulation of cell morphology.,similarity:Belongs to the small GTPase superfamily. Rho family.,subunit:Interacts with the CRIB domains of proteins such as Pak1 and Was/Wasp.,
基因名称(Gene Name)
RHOJ ARHJ RASL7B RHOI TCL
蛋白名称
Rho-related GTP-binding protein RhoJ (Ras-like protein family member 7B) (Tc10-like GTP-binding protein)
Fields
>>Salmonella infection
细胞定位
Cell membrane ; Lipid-anchor ; Cytoplasmic side . Localization to the plasma membrane is regulated by GLUL. .
组织表达
Specifically expressed in endothelial cells in different tissues, such as brain, heart, lung and liver.