免疫原
Synthesized peptide derived from human protein . at AA range: 50-130
特异性
RAB1A Polyclonal Antibody detects endogenous levels of protein.
来源
Polyclonal, Rabbit,IgG
组成(Formulation)
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
稀释比例
WB 1:500-2000 ELISA 1:5000-20000
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
背景(Background)
This gene encodes a member of the Ras superfamily of GTPases. Members of the gene family cycle between inactive GDP-bound and active GTP-bound forms. This small GTPase controls vesicle traffic from the endoplasmic reticulum to the Golgi apparatus. Multiple alternatively spliced transcript variants have been identified for this gene which encode different protein isoforms. [provided by RefSeq, Oct 2008],
功能
function:Probably required for transit of protein from the ER through Golgi compartment. Binds GTP and GDP and possesses intrinsic GTPase activity.,PTM:Phosphorylated by CDC2 kinase during mitosis.,similarity:Belongs to the small GTPase superfamily. Rab family.,subunit:May interact with YIPF5.,
基因名称(Gene Name)
RAB1A RAB1
蛋白名称
Ras-related protein Rab-1A (YPT1-related protein)
Fields
>>Autophagy - animal;>>Amyotrophic lateral sclerosis;>>Pathways of neurodegeneration - multiple diseases;>>Pathogenic Escherichia coli infection;>>Legionellosis
细胞定位
Golgi apparatus . Endoplasmic reticulum . Early endosome . Cytoplasm, cytosol . Membrane . Melanosome . Alternates between membrane-associated and cytosolic forms. .
组织表达
Brain,Colon,Placenta,Platelet,Tongue,