免疫原
Synthesized peptide derived from human protein . at AA range: 90-170
特异性
R51A1 Polyclonal Antibody detects endogenous levels of protein.
来源
Polyclonal, Rabbit,IgG
组成（Formulation）
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
稀释比例
WB 1:500-2000 ELISA 1:5000-20000
纯化工艺（Immunogen）
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
背景（Background）
alternative products:Additional isoforms seem to exist,function:May participate in a common DNA damage response pathway associated with the activation of homologous recombination and double-strand break repair. Binds to single and double stranded DNA, and is capable of aggregating DNA. Also binds RNA.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,subcellular location:Colocalizes with RAD51 to multiple nuclear foci.,subunit:Isoform 2 interacts with RAD51.,tissue specificity:Highly expressed in testis and thymus. Lower levels in colon and small intestine. Little or no expression in spleen, prostate, ovary and peripheral blood leukocytes.,
功能
alternative products:Additional isoforms seem to exist,function:May participate in a common DNA damage response pathway associated with the activation of homologous recombination and double-strand break repair. Binds to single and double stranded DNA, and is capable of aggregating DNA. Also binds RNA.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,subcellular location:Colocalizes with RAD51 to multiple nuclear foci.,subunit:Isoform 2 interacts with RAD51.,tissue specificity:Highly expressed in testis and thymus. Lower levels in colon and small intestine. Little or no expression in spleen, prostate, ovary and peripheral blood leukocytes.,
基因名称（Gene Name）
RAD51AP1 PIR51
蛋白名称
RAD51-associated protein 1 (RAD51-interacting protein)
细胞定位
Chromosome . Nucleus . Chromosome, telomere . Colocalizes with RAD51 to multiple nuclear foci (By similarity). Colocalizes with DMC1 on meiotic chromatin (By similarity). .
组织表达
Highly expressed in testis and thymus (PubMed:9396801). Lower levels in colon and small intestine (PubMed:9396801). Little or no expression in spleen, prostate, ovary and peripheral blood leukocytes (PubMed:9396801).
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