免疫原
Synthesized peptide derived from human protein . at AA range: 380-460
特异性
SC65 Polyclonal Antibody detects endogenous levels of protein.
来源
Polyclonal, Rabbit,IgG
组成(Formulation)
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
稀释比例
WB 1:500-2000 ELISA 1:5000-20000
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
背景(Background)
This nucleolar protein was first characterized because it was an autoantigen in cases on interstitial cystitis. The protein, with a predicted molecular weight of 50 kDa, appears to be localized in the particulate compartment of the interphase nucleolus, with a distribution distinct from that of nucleolar protein B23. During mitosis it is associated with chromosomes. [provided by RefSeq, Jul 2008],
功能
similarity:Belongs to the CRTAP/No55 family.,subcellular location:Localized uniformly throughout the granular component of the nucleolus and on the surface of chromosomes during mitosis.,
基因名称(Gene Name)
LEPREL4 NOL55 SC65
蛋白名称
Synaptonemal complex protein SC65 (Leprecan-like protein 4) (Nucleolar autoantigen No55)
细胞定位
Endoplasmic reticulum .
组织表达
Detected in fibroblasts (at protein level) (PubMed:23959653). Detected in spleen, prostate, testis, ovary, colon, pancreas, kidney, placenta and heart (PubMed:10952778).