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IK1 Polyclonal Antibody

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BYab-16430

  • 20UL ¥460 50UL ¥945 100UL ¥1350
  • 货期: 3天左右

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宿主
反应性
应用
WB;ELISA
分子量(DA)
48kD
免疫原
The antiserum was produced against synthesized peptide derived from human KCNN4. AA range:331-380
特异性
IK1 Polyclonal Antibody detects endogenous levels of IK1 protein.
来源
Polyclonal, Rabbit,IgG
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
浓度
1 mg/ml
背景(Background)
potassium calcium-activated channel subfamily N member 4(KCNN4) Homo sapiens The protein encoded by this gene is part of a potentially heterotetrameric voltage-independent potassium channel that is activated by intracellular calcium. Activation is followed by membrane hyperpolarization, which promotes calcium influx. The encoded protein may be part of the predominant calcium-activated potassium channel in T-lymphocytes. This gene is similar to other KCNN family potassium channel genes, but it differs enough to possibly be considered as part of a new subfamily. [provided by RefSeq, Jul 2008],
功能
function:Forms a voltage-independent potassium channel that is activated by intracellular calcium. Activation is followed by membrane hyperpolarization which promotes calcium influx. The channel is blocked by clotrimazole and charybdotoxin but is insensitive to apamin.,induction:Up-regulated by phorbol myristate acetate (PMA) and phytohemagglutinin (PHA) in T-cells.,similarity:Belongs to the potassium channel KCNN family.,subunit:Heterotetramer of potassium channel proteins (Probable). Interacts with MTMR6.,tissue specificity:Widely expressed in non-excitable tissues.,
基因名称(Gene Name)
KCNN4
蛋白名称
Intermediate conductance calcium-activated potassium channel protein 4
简称
IK1
其他名称
KCNN4; IK1; IKCA1; KCA4; SK4; Intermediate conductance calcium-activated potassium channel protein 4; SK4; SKCa 4; SKCa4; IKCa1; IK1; KCa3.1; KCa4; Putative Gardos channel
Fields
>>Insulin secretion;>>GnRH secretion;>>Salivary secretion;>>Protein digestion and absorption
人基因ID
3783
人蛋白质序列数据库
O15554
小鼠基因ID
16534
小鼠蛋白质序列数据库
O89109
大鼠基因ID
大鼠蛋白质序列数据库
Q9QYW1
细胞定位
Cell membrane ; Multi-pass membrane protein .
组织表达
Widely expressed in non-excitable tissues.
储存(Storage)
-20°C/1 year

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IK1 Polyclonal Antibody

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