免疫原
Synthesized peptide derived from human protein . at AA range: 450-530
特异性
GPM6B Polyclonal Antibody detects endogenous levels of protein.
来源
Polyclonal, Rabbit,IgG
组成(Formulation)
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
稀释比例
WB 1:500-2000 ELISA 1:5000-20000
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
背景(Background)
glycoprotein M6B(GPM6B) Homo sapiens This gene encodes a membrane glycoprotein that belongs to the proteolipid protein family. Proteolipid protein family members are expressed in most brain regions and are thought to be involved in cellular housekeeping functions such as membrane trafficking and cell-to-cell communication. This protein may also be involved in osteoblast differentiation. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are located on chromosomes Y and 22. [provided by RefSeq, Jan 2016],
功能
function:May be involved in neural development.,similarity:Belongs to the myelin proteolipid protein family.,tissue specificity:Neurons and glia; cerebellar Bergmann glia, in glia within white matter tracts of the cerebellum and cerebrum, and in embryonic dorsal root ganglia.,
基因名称(Gene Name)
GPM6B M6B
蛋白名称
Neuronal membrane glycoprotein M6-b (M6b)
细胞定位
Cell membrane ; Multi-pass membrane protein . Colocalizes with SERT at the plasma membrane. .
组织表达
Neurons and glia; cerebellar Bergmann glia, in glia within white matter tracts of the cerebellum and cerebrum, and in embryonic dorsal root ganglia.