免疫原
Synthesized peptide derived from human protein . at AA range: 1120-1200
特异性
MYO5B Polyclonal Antibody detects endogenous levels of protein.
来源
Polyclonal, Rabbit,IgG
组成(Formulation)
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
稀释比例
WB 1:500-2000 ELISA 1:5000-20000
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
背景(Background)
The protein encoded by this gene, together with other proteins, may be involved in plasma membrane recycling. Mutations in this gene are associated with microvillous inclusion disease. [provided by RefSeq, Sep 2009],
功能
disease:Defects in MYO5B are a cause of microvillus inclusion disease (MVID) [MIM:251850]. MVID is characterized by onset of intractable life-threatening watery diarrhea during infancy. Two forms are recognized: early-onset MVID with diarrhea beginning in the neonatal period, and late-onset, with first symptoms appearing after 3 or 4 months of life.,similarity:Contains 1 dilute domain.,similarity:Contains 1 myosin head-like domain.,similarity:Contains 6 IQ domains.,subunit:Interacts with RAB11FIP2.,
基因名称(Gene Name)
MYO5B KIAA1119
蛋白名称
Unconventional myosin-Vb
Fields
>>Pathogenic Escherichia coli infection