免疫原
The antiserum was produced against synthesized peptide derived from human Cytochrome P450 20A1. AA range:191-240
特异性
CYP20A1 Polyclonal Antibody detects endogenous levels of CYP20A1 protein.
来源
Polyclonal, Rabbit,IgG
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
背景(Background)
cytochrome P450 family 20 subfamily A member 1(CYP20A1) Homo sapiens This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases that catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein lacks one amino acid of the conserved heme binding site. It also lacks the conserved I-helix motif AGX(D,E)T, suggesting that its substrate may carry its own oxygen. [provided by RefSeq, Jul 2008],
功能
catalytic activity:RH + reduced flavoprotein + O(2) = ROH + oxidized flavoprotein + H(2)O.,cofactor:Heme group.,similarity:Belongs to the cytochrome P450 family.,
蛋白名称
Cytochrome P450 20A1
其他名称
CYP20A1; Cytochrome P450 20A1
细胞定位
Membrane ; Single-pass membrane protein .
组织表达
Blood,Lung,Pheochromocytoma,Placenta,Stomach,