免疫原
Synthesized peptide derived from part region of human protein
特异性
CNDP2 Polyclonal Antibody detects endogenous levels of protein.
来源
Polyclonal, Rabbit,IgG
组成(Formulation)
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
稀释比例
WB 1:500-2000 ELISA 1:5000-20000
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
背景(Background)
CNDP dipeptidase 2 (metallopeptidase M20 family)(CNDP2) Homo sapiens CNDP2, also known as tissue carnosinase and peptidase A (EC 3.4.13.18), is a nonspecific dipeptidase rather than a selective carnosinase (Teufel et al., 2003 [PubMed 12473676]).[supplied by OMIM, Mar 2008],
功能
cofactor:Binds 2 zinc ions per subunit.,similarity:Belongs to the peptidase M20A family.,
基因名称(Gene Name)
CNDP2 CN2 CPGL PEPA
蛋白名称
Cytosolic non-specific dipeptidase (EC 3.4.13.18) (CNDP dipeptidase 2) (Glutamate carboxypeptidase-like protein 1) (Peptidase A)
Fields
>>Arginine and proline metabolism;>>Histidine metabolism;>>beta-Alanine metabolism;>>Metabolic pathways
组织表达
[Isoform 1]: Ubiquitously expressed with higher levels in kidney and liver (at protein level). Expressed in peripheral blood leukocytes (PubMed:12473676). Expressed in gastric mucosa and down-regulated in gastric cancer mucosal tissues (at protein level) (PubMed:24395568). ; [Isoform 2]: Broadly expressed in fetal tissues. Expressed in adult liver and placenta.