免疫原
Synthesized peptide derived from part region of human protein
特异性
BORG5 Polyclonal Antibody detects endogenous levels of protein.
来源
Polyclonal, Rabbit,IgG
组成（Formulation）
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
稀释比例
WB 1:500-2000 ELISA 1:5000-20000
纯化工艺（Immunogen）
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
背景（Background）
CDC42 is a member of the Rho GTPase family that regulates multiple cellular activities, including actin polymerization. The protein encoded by this gene is a CDC42 binding protein that mediates actin cytoskeleton reorganization at the plasma membrane. This protein is secreted and is primarily found in bone marrow. [provided by RefSeq, Jul 2008],
功能
domain:The CRIB domain mediates interaction with CDC42.,function:Probably involved in the organization of the actin cytoskeleton. Induced membrane extensions in fibroblasts.,similarity:Belongs to the BORG/CEP family.,similarity:Contains 1 CRIB domain.,subunit:Interacts with RHOQ and CDC42, in a GTP-dependent manner.,tissue specificity:Endothelial and bone marrow stromal cells.,
基因名称（Gene Name）
CDC42EP1 BORG5 CEP1 MSE55
蛋白名称
Cdc42 effector protein 1 (Binder of Rho GTPases 5) (Serum protein MSE55)
细胞定位
Endomembrane system ; Peripheral membrane protein . Cytoplasm, cytoskeleton .
组织表达
Endothelial and bone marrow stromal cells.
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