免疫原
Synthesized peptide derived from human protein . at AA range: 200-280
特异性
B2L14 Polyclonal Antibody detects endogenous levels of protein.
来源
Polyclonal, Rabbit,IgG
组成(Formulation)
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
稀释比例
WB 1:500-2000 ELISA 1:5000-20000
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
背景(Background)
The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. Overexpression of this gene has been shown to induce apoptosis in cells. Three alternatively spliced transcript variants encoding two distinct isoforms have been reported for this gene. [provided by RefSeq, May 2009],
功能
function:May play a role in apoptosis.,similarity:Belongs to the Bcl-2 family.,subcellular location:Diffusely distributed throughout the cytosol.,subcellular location:Predominantly localized to cytosolic organelles.,tissue specificity:Isoform 1 is widely expressed and isoform 2 is testis-specific.,
基因名称(Gene Name)
BCL2L14 BCLG
蛋白名称
Apoptosis facilitator Bcl-2-like protein 14 (Bcl2-L-14) (Apoptosis regulator Bcl-G)
细胞定位
Cytoplasm .; [Isoform 1]: Cytoplasm, cytosol. Diffusely distributed throughout the cytosol.; [Isoform 2]: Endomembrane system. Predominantly localized to cytosolic organelles.
组织表达
Isoform 1 is widely expressed. Isoform 2 is testis-specific.