免疫原
Synthesized peptide derived from human protein . at AA range: 1-80
特异性
CALY Polyclonal Antibody detects endogenous levels of protein.
来源
Polyclonal, Rabbit,IgG
组成（Formulation）
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
稀释比例
WB 1:500-2000 ELISA 1:5000-20000
纯化工艺（Immunogen）
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
背景（Background）
calcyon neuron specific vesicular protein(CALY) Homo sapiens The protein encoded by this gene is a type II single transmembrane protein. It is required for maximal stimulated calcium release after stimulation of purinergic or muscarinic but not beta-adrenergic receptors. The encoded protein interacts with D1 dopamine receptor and may interact with other DA receptor subtypes and/or GPCRs. [provided by RefSeq, Jul 2008],
功能
caution:Was originally (PubMed:10698743) thought to interact with the D1 dopamine receptor (DRD1) and to play a role in potentiating calcium ion-dependent signaling but this work was later retracted.,function:Interacts with clathrin light chain A and stimulates clathrin self-assembly and clathrin-mediated endocytosis.,PTM:Glycosylated.,similarity:Belongs to the NSG family.,subunit:Interacts with CLTA.,tissue specificity:Expressed in the pyramidal cells of the prefrontal cortex, in hippothalamus and in caudate nucleus. No expression in spleen. Up-regulated in the prefrontal cortex of schizophrenic patients with nearly twice the levels of non-schizophrenics.,
基因名称（Gene Name）
CALY DRD1IP
蛋白名称
Neuron-specific vesicular protein calcyon
Fields
>>Dopaminergic synapse
细胞定位
Cytoplasmic vesicle membrane; Single-pass membrane protein. Cell membrane; Single-pass membrane protein.
组织表达
Expressed in the pyramidal cells of the prefrontal cortex, in hippothalamus and in caudate nucleus. No expression in spleen. Up-regulated in the prefrontal cortex of schizophrenic patients with nearly twice the levels of non-schizophrenics.
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