免疫原
The antiserum was produced against synthesized peptide derived from human T3JAM. AA range:251-300
特异性
T3JAM Polyclonal Antibody detects endogenous levels of T3JAM protein.
来源
Polyclonal, Rabbit,IgG
组成（Formulation）
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.
纯化工艺（Immunogen）
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
背景（Background）
The gene encodes a protein that mediates cell growth by modulating the c-Jun N-terminal kinase signal transduction pathway. The encoded protein may also interact with a large multi-protein assembly containing the phosphatase 2A catalytic subunit. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013],
功能
function:May function as an adapter molecule that regulates TRAF3-mediated JNK activation.,subunit:Binds to the isoleucine zipper of TRAF3 via its coiled-coil domain.,
蛋白名称
TRAF3-interacting JNK-activating modulator
其他名称
TRAF3IP3; T3JAM; TRAF3-interacting JNK-activating modulator; TRAF3-interacting protein 3
细胞定位
Cell membrane . Golgi apparatus membrane ; Single-pass type IV membrane protein . Lysosome membrane . Mitochondrion outer membrane . Accumulates on the mitochondria after virus infection. .
组织表达
Blood,Lung adenocarcinoma,
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