免疫原
Synthesized peptide derived from part region of human protein
特异性
DLL4 Polyclonal Antibody detects endogenous levels of protein.
来源
Polyclonal, Rabbit,IgG
组成（Formulation）
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
稀释比例
WB 1:500-2000 ELISA 1:5000-20000
纯化工艺（Immunogen）
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
背景（Background）
This gene is a homolog of the Drosophila delta gene. The delta gene family encodes Notch ligands that are characterized by a DSL domain, EGF repeats, and a transmembrane domain. [provided by RefSeq, Jul 2008],
功能
domain:The Delta-Serrate-Lag2 (DSL) domain is required for binding to the Notch receptor.,function:Plays a role in the Notch signaling pathway. Activates Notch-1 and Notch-4.,PTM:Ubiquitinated by MIB (MIB1 or MIB2), leading to its endocytosis and subsequent degradation.,similarity:Contains 1 DSL domain.,similarity:Contains 8 EGF-like domains.,subunit:Binds to Notch-1 and Notch-4.,tissue specificity:Expressed in vascular endothelium.,
基因名称（Gene Name）
DLL4 UNQ1895/PRO4341
蛋白名称
Delta-like protein 4 (Drosophila Delta homolog 4) (Delta4)
Fields
>>Endocrine resistance;>>Notch signaling pathway;>>Th1 and Th2 cell differentiation;>>Pathways in cancer;>>Chemical carcinogenesis - receptor activation;>>Breast cancer
细胞定位
Cell membrane ; Single-pass type I membrane protein .
组织表达
Expressed in vascular endothelium.
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