免疫原
The antiserum was produced against synthesized peptide derived from human RPL14. AA range:71-120
特异性
Ribosomal Protein L14 Polyclonal Antibody detects endogenous levels of Ribosomal Protein L14 protein.
来源
Polyclonal, Rabbit,IgG
组成（Formulation）
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
纯化工艺（Immunogen）
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
背景（Background）
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L14E family of ribosomal proteins. It contains a basic region-leucine zipper (bZIP)-like domain. The protein is located in the cytoplasm. This gene contains a trinucleotide (GCT) repeat tract whose length is highly polymorphic; these triplet repeats result in a stretch of alanine residues in the encoded protein. Transcript variants utilizing alternative polyA signals and alternative 5'-terminal exons exist but all encode the same protein. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.
功能
polymorphism:The poly-Ala stretch is highly polymorphic.,similarity:Belongs to the ribosomal protein L14e family.,
蛋白名称
60S ribosomal protein L14
其他名称
RPL14; 60S ribosomal protein L14; CAG-ISL 7
Fields
>>Ribosome;>>Coronavirus disease - COVID-19
细胞定位
cytoplasm,cytosol,ribosome,cell-cell adherens junction,membrane,cytosolic large ribosomal subunit,extracellular exosome,
组织表达
Brain,Cervix carcinoma,Dermoid cancer,Epithelium,Kidney,Muscle,Ovary,Pancreas,Skin,
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