免疫原
The antiserum was produced against synthesized peptide derived from human RGS5. AA range:89-138
特异性
RGS5 Polyclonal Antibody detects endogenous levels of RGS5 protein.
来源
Polyclonal, Rabbit,IgG
组成（Formulation）
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
WB: 1/500 - 1/2000. IHC: 1/100 - 1/300. ELISA: 1/20000.. IF 1:50-200
纯化工艺（Immunogen）
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
背景（Background）
This gene encodes a member of the regulators of G protein signaling (RGS) family. The RGS proteins are signal transduction molecules which are involved in the regulation of heterotrimeric G proteins by acting as GTPase activators. This gene is a hypoxia-inducible factor-1 dependent, hypoxia-induced gene which is involved in the induction of endothelial apoptosis. This gene is also one of three genes on chromosome 1q contributing to elevated blood pressure. Alternatively spliced transcript variants have been identified. [provided by RefSeq, Dec 2011],
功能
function:Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Binds to G(i)-alpha and G(o)-alpha, but not to G(s)-alpha.,similarity:Contains 1 RGS domain.,
蛋白名称
Regulator of G-protein signaling 5
其他名称
RGS5; Regulator of G-protein signaling 5; RGS5
细胞定位
[Isoform 1]: Cytoplasm . Membrane .; [Isoform 2]: Cytoplasm .
组织表达
Aorta,Brain,Human cervix,Liver,Neuroblastoma,Normal aorta,
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