免疫原
The antiserum was produced against synthesized peptide derived from human HSPB2. AA range:121-170
特异性
HSP β2 Polyclonal Antibody detects endogenous levels of HSP β2 protein.
来源
Polyclonal, Rabbit,IgG
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/40000. Not yet tested in other applications.
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
背景(Background)
The protein encoded by this gene belongs to the superfamily of small heat-shock proteins containing a conservative alpha-crystallin domain at the C-terminal part of the molecule. The protein is expressed preferentially in the heart and skeletal muscle. This protein regulates Myotonic Dystrophy Protein Kinase, which plays an important role in maintenance of muscle structure and function. [provided by RefSeq, Dec 2012],
功能
similarity:Belongs to the small heat shock protein (HSP20) family.,subunit:Associates specifically with myotonic dystrophy protein kinase (DMPK).,tissue specificity:Expressed preferentially in skeletal muscle and heart but not in the lens.,
蛋白名称
Heat shock protein beta-2
其他名称
HSPB2; Heat shock protein beta-2; HspB2; DMPK-binding protein; MKBP
Fields
>>Proteoglycans in cancer
细胞定位
Cytoplasm . Nucleus . Localizes to nuclear foci.
组织表达
Expressed preferentially in skeletal muscle and heart but not in the lens.