免疫原
Synthesized peptide derived from the Internal region of human Glypican-5.
特异性
Glypican-5 Polyclonal Antibody detects endogenous levels of Glypican-5 protein.
来源
Polyclonal, Rabbit,IgG
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
背景(Background)
Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation. [provided by RefSeq, Jul 2008],
功能
function:Cell surface proteoglycan that bears heparan sulfate.,similarity:Belongs to the glypican family.,tissue specificity:In adult, primarily expressed in the brain. Also detected in fetal brain, lung and liver.,
细胞定位
Cell membrane ; Lipid-anchor, GPI-anchor ; Extracellular side .; [Secreted glypican-5]: Secreted, extracellular space .
组织表达
In adult, primarily expressed in the brain. Also detected in fetal brain, lung and liver.