免疫原
The antiserum was produced against synthesized peptide derived from human GCS-beta-2. AA range:53-102
特异性
GCS-β-2 Polyclonal Antibody detects endogenous levels of GCS-β-2 protein.
来源
Polyclonal, Rabbit,IgG
组成（Formulation）
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
IHC: 1/100 - 1/300. ELISA: 1/10000.. IF 1:50-200
纯化工艺（Immunogen）
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
背景（Background）
Nitric oxide-sensitive guanylyl cyclase is a heterodimeric enzyme consisting of an alpha and a beta subunit. The enzyme converts GTP into the second messenger cGMP and plays a major role in the cardiovascular system as a receptor for nitric oxide. Unlike other guanylyl cyclases, GUCY1B2 contains an 86-amino acid C-terminal extension with a consensus sequence for isoprenylation/carboxymethylation.
蛋白名称
Guanylate cyclase soluble subunit beta-2
其他名称
GUCY1B2; Guanylate cyclase soluble subunit beta-2; GCS-beta-2
组织表达
Expressed in gastric signet ring cell carcinoma, but not in the normal stomach.
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