免疫原
The antiserum was produced against synthesized peptide derived from human DKK3. AA range:111-160
特异性
Dkk-3 Polyclonal Antibody detects endogenous levels of Dkk-3 protein.
来源
Polyclonal, Rabbit,IgG
组成（Formulation）
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.
纯化工艺（Immunogen）
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
背景（Background）
This gene encodes a protein that is a member of the dickkopf family. The secreted protein contains two cysteine rich regions and is involved in embryonic development through its interactions with the Wnt signaling pathway. The expression of this gene is decreased in a variety of cancer cell lines and it may function as a tumor suppressor gene. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Jul 2008],
功能
function:Inhibitor of Wnt signaling pathway .,PTM:N-glycosylated.,similarity:Belongs to the dickkopf family.,tissue specificity:Highest expression in heart, brain, and spinal cord.,
蛋白名称
Dickkopf-related protein 3
其他名称
DKK3; REIC; Dickkopf-related protein 3; Dickkopf-3; Dkk-3; hDkk-3
组织表达
Highest expression in heart, brain, and spinal cord.
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