免疫原
The antiserum was produced against synthesized peptide derived from human CEP152. AA range:841-890
特异性
CEP152 Polyclonal Antibody detects endogenous levels of CEP152 protein.
来源
Polyclonal, Rabbit,IgG
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
WB: 1/500 - 1/2000. IHC: 1/100 - 1/300. ELISA: 1/40000.. IF 1:50-200
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
背景(Background)
centrosomal protein 152(CEP152) Homo sapiens This gene encodes a protein that is thought to be involved with centrosome function. Mutations in this gene have been associated with primary microcephaly (MCPH4). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2010],
功能
sequence caution:Contaminating sequence. Potential poly-A sequence.,
蛋白名称
Centrosomal protein of 152 kDa
其他名称
CEP152; KIAA0912; Centrosomal protein of 152 kDa; Cep152
细胞定位
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole . Colocalizes with CDK5RAP2, WDR62 and CEP63 in a discrete ring around the proximal end of the parental centriole. At this site, a cohesive structure is predicted to engage parental centrioles and procentrioles (PubMed:21983783, PubMed:26297806). Localizes to the deuterosome (By similarity). Localizes to pericentriolar material (PCM) (PubMed:26337392). .
组织表达
Bladder,Brain,Heart,Lung,Testis,