免疫原
The antiserum was produced against synthesized peptide derived from human AHSA1. AA range:161-210
特异性
AHA-1 Polyclonal Antibody detects endogenous levels of AHA-1 protein.
来源
Polyclonal, Rabbit,IgG
组成（Formulation）
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
WB: 1/500 - 1/2000. IHC: 1/100 - 1/300;ELISA 1:5000-20000.. IF 1:50-200
纯化工艺（Immunogen）
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
背景（Background）
function:Cochaperone that stimulates HSP90 ATPase activity (By similarity). May affect a step in the endoplasmic reticulum to Golgi trafficking.,induction:By heat shock and treatment with the HSP90 inhibitor 17-demethoxygeldanamycin (17AAG).,similarity:Belongs to the AHA1 family.,subcellular location:May transiently interact with the endoplasmic reticulum.,subunit:Interacts with HSPCA/HSP90 and with the cytoplasmic tail of the vesicular stomatitis virus glycoprotein (VSV G). Interacts with GCH1.,tissue specificity:Expressed in numerous tissues, including brain, heart, skeletal muscle and kidney and, at lower levels, liver and placenta.,
功能
function:Cochaperone that stimulates HSP90 ATPase activity (By similarity). May affect a step in the endoplasmic reticulum to Golgi trafficking.,induction:By heat shock and treatment with the HSP90 inhibitor 17-demethoxygeldanamycin (17AAG).,similarity:Belongs to the AHA1 family.,subcellular location:May transiently interact with the endoplasmic reticulum.,subunit:Interacts with HSPCA/HSP90 and with the cytoplasmic tail of the vesicular stomatitis virus glycoprotein (VSV G). Interacts with GCH1.,tissue specificity:Expressed in numerous tissues, including brain, heart, skeletal muscle and kidney and, at lower levels, liver and placenta.,
蛋白名称
Activator of 90 kDa heat shock protein ATPase homolog 1
其他名称
AHSA1; C14orf3; HSPC322; Activator of 90 kDa heat shock protein ATPase homolog 1; AHA1; p38
细胞定位
Cytoplasm, cytosol . Endoplasmic reticulum . May transiently interact with the endoplasmic reticulum.
组织表达
Expressed in numerous tissues, including brain, heart, skeletal muscle and kidney and, at lower levels, liver and placenta.
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