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MARCKS (phospho Ser163) Polyclonal Antibody

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BYab-03608

  • 20UL ¥460 50UL ¥945 100UL ¥1350
  • 货期: 3天左右

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宿主
反应性
应用
IHC;IF;ELISA
分子量(DA)
免疫原
The antiserum was produced against synthesized peptide derived from human MARCKS around the phosphorylation site of Ser163. AA range:136-185
特异性
Phospho-MARCKS (S163) Polyclonal Antibody detects endogenous levels of MARCKS protein only when phosphorylated at S163.
来源
Polyclonal, Rabbit,IgG
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
IHC: 1/100 - 1/300. ELISA: 1/10000.. IF 1:50-200
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
浓度
1 mg/ml
背景(Background)
The protein encoded by this gene is a substrate for protein kinase C. It is localized to the plasma membrane and is an actin filament crosslinking protein. Phosphorylation by protein kinase C or binding to calcium-calmodulin inhibits its association with actin and with the plasma membrane, leading to its presence in the cytoplasm. The protein is thought to be involved in cell motility, phagocytosis, membrane trafficking and mitogenesis. [provided by RefSeq, Jul 2008],
功能
function:MARCKS is the most prominent cellular substrate for protein kinase C. This protein binds calmodulin, actin, and synapsin. MARCKS is a filamentous (F) actin cross-linking protein.,PTM:Phosphorylation by PKC displaces MARCKS from the membrane. It also inhibits the F-actin cross-linking activity.,similarity:Belongs to the MARCKS family.,
基因名称(Gene Name)
MARCKS
蛋白名称
Myristoylated alanine-rich C-kinase substrate
简称
MARCKS
其他名称
MARCKS; MACS; PRKCSL; Myristoylated alanine-rich C-kinase substrate; MARCKS; Protein kinase C substrate; 80 kDa protein, light chain; 80K-L protein; PKCSL
Fields
>>Fc gamma R-mediated phagocytosis;>>MicroRNAs in cancer
人基因ID
4082
人蛋白质序列数据库
P29966
小鼠基因ID
17118
小鼠蛋白质序列数据库
P26645
大鼠基因ID
大鼠蛋白质序列数据库
P30009
细胞定位
Cytoplasm, cytoskeleton . Membrane ; Lipid-anchor .
组织表达
Blood,Brain,Epithelium,Muscle,Skin,
储存(Storage)
-20°C/1 year

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MARCKS (phospho Ser163) Polyclonal Antibody

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