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Protein Z Monoclonal Antibody

说明书

BYab-03415

  • 20UL ¥460 50UL ¥945 100UL ¥1350
  • 货期: 3天左右

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宿主
反应性
应用
WB;ELISA
分子量(DA)
免疫原
Purified recombinant fragment of Protein Z expressed in E. Coli.
特异性
Protein Z Monoclonal Antibody detects endogenous levels of Protein Z protein.
来源
Monoclonal, Mouse
组成(Formulation)
Ascitic fluid containing 0.03% sodium azide,0.5% BSA, 50%glycerol.
稀释比例
Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
纯化工艺(Immunogen)
Affinity purification
浓度
背景(Background)
This gene encodes a liver vitamin K-dependent glycoprotein that is synthesized in the liver and secreted into the plasma. The encoded protein plays a role in regulating blood coagulation by complexing with protein Z-dependent protease inhibitor to directly inhibit activated factor X at the phospholipid surface. Deficiencies in this protein are associated with an increased risk of ischemic arterial diseases and fetal loss. Mutations in this gene are the cause of protein Z deficiency. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2012],
功能
caution:Although homologous with the vitamin K-dependent clotting factors, it has lost two of the essential catalytic residues and has no enzymatic activity.,function:Appears to assist hemostasis by binding thrombin and promoting its association with phospholipid vesicles.,PTM:The iron and 2-oxoglutarate dependent 3-hydroxylation of aspartate and asparagine is (R) stereospecific within EGF domains.,similarity:Belongs to the peptidase S1 family.,similarity:Contains 1 Gla (gamma-carboxy-glutamate) domain.,similarity:Contains 1 peptidase S1 domain.,similarity:Contains 2 EGF-like domains.,tissue specificity:Plasma.,
基因名称(Gene Name)
PROZ
蛋白名称
Vitamin K-dependent protein Z
简称
Protein Z
其他名称
PROZ; Vitamin K-dependent protein Z
Fields
人基因ID
8858
人蛋白质序列数据库
P22891
小鼠基因ID
小鼠蛋白质序列数据库
Q9CQW3
大鼠基因ID
大鼠蛋白质序列数据库
细胞定位
Secreted.
组织表达
Plasma.
储存(Storage)
-20°C/1 year

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Protein Z Monoclonal Antibody

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