免疫原
Synthesized peptide derived from Myosin XVI . at AA range: 1050-1130
特异性
Myosin XVI Polyclonal Antibody detects endogenous levels of Myosin XVI protein.
来源
Polyclonal, Rabbit,IgG
组成（Formulation）
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
纯化工艺（Immunogen）
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
背景（Background）
function:Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Their highly divergent tails are presumed to bind to membranous compartments, which would be moved relative to actin filaments. May be involved in targeting of the catalytic subunit of protein phosphatase 1 during brain development.,similarity:Contains 1 IQ domain.,similarity:Contains 2 myosin head-like domains.,similarity:Contains 7 ANK repeats.,subcellular location:Found in puncta in soma and processes of astrocytes and dissociated cerebellar cells with the morphology of migrating granule cells.,subunit:Binds PPP1CA and/or PPP1CC. Binds F-actin in an ATP-sensitive manner.,
功能
function:Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Their highly divergent tails are presumed to bind to membranous compartments, which would be moved relative to actin filaments. May be involved in targeting of the catalytic subunit of protein phosphatase 1 during brain development.,similarity:Contains 1 IQ domain.,similarity:Contains 2 myosin head-like domains.,similarity:Contains 7 ANK repeats.,subcellular location:Found in puncta in soma and processes of astrocytes and dissociated cerebellar cells with the morphology of migrating granule cells.,subunit:Binds PPP1CA and/or PPP1CC. Binds F-actin in an ATP-sensitive manner.,
蛋白名称
Unconventional myosin-XVI
其他名称
MYO16; KIAA0865; MYO16B; NYAP3; Unconventional myosin-XVI; Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter 3; Unconventional myosin-16
细胞定位
Cytoplasm . Found in puncta in soma and processes of astrocytes and dissociated cerebellar cells with the morphology of migrating granule cells. .
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