免疫原
The antiserum was produced against synthesized peptide derived from human OTUB2. AA range:133-182
特异性
OTUB2 Polyclonal Antibody detects endogenous levels of OTUB2 protein.
来源
Polyclonal, Rabbit,IgG
组成（Formulation）
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
WB: 1/500 - 1/2000. IHC: 1/100 - 1/300. ELISA: 1/20000.. IF 1:50-200
纯化工艺（Immunogen）
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
背景（Background）
OTU deubiquitinase, ubiquitin aldehyde binding 2(OTUB2) Homo sapiens This gene encodes one of several deubiquitylating enzymes. Ubiquitin modification of proteins is needed for their stability and function; to reverse the process, deubiquityling enzymes remove ubiquitin. This protein contains an OTU domain and binds Ubal (ubiquitin aldehyde); an active cysteine protease site is present in the OTU domain. [provided by RefSeq, Aug 2011],
功能
function:Hydrolase that can remove conjugated ubiquitin from proteins in vitro and may therefore play an important regulatory role at the level of protein turnover by preventing degradation.,similarity:Belongs to the peptidase C65 family.,similarity:Contains 1 OTU domain.,tissue specificity:Widely expressed. Expressed at higher level in brain.,
蛋白名称
Ubiquitin thioesterase OTUB2
其他名称
OTUB2; C14orf137; OTB2; OTU2; Ubiquitin thioesterase OTUB2; Deubiquitinating enzyme OTUB2; OTU domain-containing ubiquitin aldehyde-binding protein 2; Otubain-2; Ubiquitin-specific-processing protease OTUB2
组织表达
Widely expressed. Expressed at higher level in brain.
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