免疫原
A synthesized peptide derived from Human CD32
稀释比例
FC: 5μL per test for million cells or whole blood in 100 μL volume.
背景(Background)
CD32 is a 40 kD polymorphic transmembrane glycoprotein also known as FcγRII and FCRII. It is an immunoglobulin superfamily member expressed on monocytes/macrophages, granulocytes, platelets and B cells. There are at least 6 isoforms of CD32 resulting from alternative mRNA splicing. CD32 mediates phagocytosis and oxidative burst in granulocytes, as well as platelet aggregation and immunomodulation. The extracellular domain of CD32 binds to polymeric and aggregated IgG and immune complexes, while the intracellular domain has been reported to associate with SHP-1 (B1 isoform).
其他名称
Fc fragment of IgG; low affinity IIb; receptor (CD32); CD32; FCG2; CD32B; FCGR2; IGFR2
人基因ID
SwissProt ID
P31994
储存(Storage)
Store at 2-8℃ and protected from prolonged exposure to light. Avoid freeze/thaw cycles.