免疫原
Synthesized peptide derived from SRp55 . at AA range: 30-110
特异性
SRp55 Polyclonal Antibody detects endogenous levels of SRp55 protein.
来源
Polyclonal, Rabbit,IgG
组成（Formulation）
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
IHC: 1/100 - 1/300. ELISA: 1/20000.. IF 1:50-200
纯化工艺（Immunogen）
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
背景（Background）
The protein encoded by this gene is involved in mRNA splicing and may play a role in the determination of alternative splicing. The encoded nuclear protein belongs to the splicing factor SR family and has been shown to bind with and modulate another member of the family, SFRS12. Alternative splicing results in multiple transcript variants. In addition, two pseudogenes, one on chromosome 17 and the other on the X chromosome, have been found for this gene.[provided by RefSeq, Sep 2010],
功能
function:Plays a role in constitutive splicing and can modulate the selection of alternative splice sites.,PTM:Extensively phosphorylated on serine residues in the RS domain.,similarity:Belongs to the splicing factor SR family.,similarity:Contains 2 RRM (RNA recognition motif) domains.,subunit:Binds SFRS12.,
蛋白名称
Serine/arginine-rich splicing factor 6
其他名称
SRSF6; SFRS6; SRP55; Serine/arginine-rich splicing factor 6; Pre-mRNA-splicing factor SRP55; Splicing factor; arginine/serine-rich 6
Fields
>>Spliceosome;>>Herpes simplex virus 1 infection
细胞定位
Nucleus . Nucleus speckle .
组织表达
Brain,Colon,Epithelium,Placenta,
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