免疫原
The antiserum was produced against synthesized peptide derived from human NUCKS1. AA range:28-77
特异性
NUCKS Polyclonal Antibody detects endogenous levels of NUCKS protein.
来源
Polyclonal, Rabbit,IgG
组成（Formulation）
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
IHC: 1/100 - 1/300. ELISA: 1/10000.. IF 1:50-200
纯化工艺（Immunogen）
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
背景（Background）
This gene encodes a nuclear protein that is highly conserved in vertebrates. The conserved regions of the protein contain several consensus phosphorylation sites for casein kinase II and cyclin-dependent kinases, two putative nuclear localization signals, and a basic DNA-binding domain. It is phosphorylated in vivo by Cdk1 during mitosis of the cell cycle. [provided by RefSeq, Aug 2010],
功能
PTM:Phosphorylated by CDK1 and casein kinase. Phosphorylated upon DNA damage, probably by ATM or ATR.,sequence caution:Translated as Arg.,
蛋白名称
Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1
其他名称
NUCKS1; NUCKS; JC7; Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1; P1
细胞定位
Nucleus . Chromosome .
组织表达
Widely expressed, with highest levels in thyroid gland, prostate and uterus and in fetal liver, thymus and lung.
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