免疫原
The antiserum was produced against synthesized peptide derived from human C1orf57. AA range:141-190
特异性
NTPase Polyclonal Antibody detects endogenous levels of NTPase protein.
来源
Polyclonal, Rabbit,IgG
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
WB: 1/500 - 1/2000. IHC: 1/100 - 1/300. ELISA: 1/40000.. IF 1:50-200
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
背景(Background)
The protein encoded by this gene is a non-specific nucleoside triphosphatase that is slow-acting in vitro. This gene is overexpressed in many tumor tissues, and while it is not essential for the cell, overexpression is cytotoxic. However, the cytotoxicity is not related to its triphosphatase activity. [provided by RefSeq, Jul 2016],
功能
catalytic activity:NTP + H(2)O = NDP + phosphate.,function:Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP. Hydrolyzes nucleoside diphosphates with lower efficiency.,similarity:Belongs to the THEP1 NTPase family.,subunit:Monomer.,
蛋白名称
Cancer-related nucleoside-triphosphatase
其他名称
NTPCR; C1orf57; Cancer-related nucleoside-triphosphatase; NTPase; Nucleoside triphosphate phosphohydrolase
Fields
>>Purine metabolism;>>Thiamine metabolism;>>Metabolic pathways;>>Nucleotide metabolism
细胞定位
membrane,extracellular exosome,