免疫原
The antiserum was produced against synthesized peptide derived from human ECP. AA range:102-151
特异性
ECP Polyclonal Antibody detects endogenous levels of ECP protein.
来源
Polyclonal, Rabbit,IgG
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
背景(Background)
The protein encoded by this gene belongs to the pancreatic ribonuclease family, a subset of the ribonuclease A superfamily. The protein exhibits antimicrobial activity against pathogenic bacteria [provided by RefSeq, Oct 2014],
功能
disease:Induces the neurotoxic effect known as the Gordon phenomenon.,function:Cytotoxin and helminthotoxin with low-efficiency ribonuclease activity. Possesses a wide variety of biological activities. Exhibits antibacterial activity.,similarity:Belongs to the pancreatic ribonuclease family.,subcellular location:Matrix of eosinophil's large specific granule.,
蛋白名称
Eosinophil cationic protein
其他名称
RNASE3; ECP; RNS3; Eosinophil cationic protein; ECP; Ribonuclease 3; RNase 3
细胞定位
Secreted. Located in the matrix of eosinophil large specific granule, which are released following activation by an immune stimulus.
组织表达
Colon,Fetal liver,Peripheral blood granulocyte,