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SNAI 1 Monoclonal Antibody

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BYab-01021

  • 20UL ¥460 50UL ¥945 100UL ¥1350
  • 货期: 3天左右

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宿主
反应性
应用
WB;ELISA
分子量(DA)
免疫原
Purified recombinant fragment of human SNAI 1 expressed in E. Coli.
特异性
SNAI 1 Monoclonal Antibody detects endogenous levels of SNAI 1 protein.
来源
Monoclonal, Mouse
组成(Formulation)
Ascitic fluid containing 0.03% sodium azide,0.5% BSA, 50%glycerol.
稀释比例
Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
纯化工艺(Immunogen)
Affinity purification
浓度
背景(Background)
snail family transcriptional repressor 1(SNAI1) Homo sapiens The Drosophila embryonic protein snail is a zinc finger transcriptional repressor which downregulates the expression of ectodermal genes within the mesoderm. The nuclear protein encoded by this gene is structurally similar to the Drosophila snail protein, and is also thought to be critical for mesoderm formation in the developing embryo. At least two variants of a similar processed pseudogene have been found on chromosome 2. [provided by RefSeq, Jul 2008],
功能
function:Seems to be involved in embryonic mesoderm formation. Binds to 3 E-boxes of the E-cadherin gene promoter and represses its transcription.,similarity:Belongs to the snail C2H2-type zinc-finger protein family.,similarity:Contains 4 C2H2-type zinc fingers.,tissue specificity:Expressed in a variety of tissues with the highest expression in kidney.,
基因名称(Gene Name)
SNAI1
蛋白名称
Zinc finger protein SNAI1(snail)
简称
SNAI1
其他名称
SNAI1; SNAH; Zinc finger protein SNAI1; Protein snail homolog 1; Protein sna
Fields
>>Adherens junction
人基因ID
6615
人蛋白质序列数据库
O95863
小鼠基因ID
小鼠蛋白质序列数据库
Q02085
大鼠基因ID
大鼠蛋白质序列数据库
细胞定位
Nucleus . Cytoplasm . Once phosphorylated (probably on Ser-107, Ser-111, Ser-115 and Ser-119) it is exported from the nucleus to the cytoplasm where subsequent phosphorylation of the destruction motif and ubiquitination involving BTRC occurs. .
组织表达
Expressed in a variety of tissues with the highest expression in kidney. Expressed in mesenchymal and epithelial cell lines.
储存(Storage)
-20°C/1 year

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SNAI 1 Monoclonal Antibody

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