免疫原
The antiserum was produced against synthesized peptide derived from human SCAMP1. AA range:273-322
特异性
SCAMP1 Polyclonal Antibody detects endogenous levels of SCAMP1 protein.
来源
Polyclonal, Rabbit,IgG
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
WB 1:500-2000;IHC-p 1:50-300
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
背景(Background)
This gene product belongs to the SCAMP family of proteins, which are secretory carrier membrane proteins. They function as carriers to the cell surface in post-golgi recycling pathways. Different family members are highly related products of distinct genes, and are usually expressed together. These findings suggest that these protein family members may function at the same site during vesicular transport rather than in separate pathways. A pseudogene of this gene has been defined on chromosome 1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014],
功能
function:Functions in post-Golgi recycling pathways. Acts as a recycling carrier to the cell surface.,similarity:Belongs to the SCAMP family.,subunit:Interacts with AP1GBP1 and ITSN1 (By similarity). Interacts with SLC9A7.,tissue specificity:Widely expressed, with highest expression in brain.,
蛋白名称
Secretory carrier-associated membrane protein 1
其他名称
SCAMP1; SCAMP; Secretory carrier-associated membrane protein 1; Secretory carrier membrane protein 1
细胞定位
Golgi apparatus, trans-Golgi network membrane ; Multi-pass membrane protein . Recycling endosome membrane ; Multi-pass membrane protein .
组织表达
Widely expressed, with highest expression in brain.