免疫原
The antiserum was produced against synthesized peptide derived from human BCLAF1. AA range:281-330
特异性
BTF Polyclonal Antibody detects endogenous levels of BTF protein.
来源
Polyclonal, Rabbit,IgG
组成（Formulation）
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
纯化工艺（Immunogen）
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
背景（Background）
This gene encodes a transcriptional repressor that interacts with several members of the BCL2 family of proteins. Overexpression of this protein induces apoptosis, which can be suppressed by co-expression of BCL2 proteins. The protein localizes to dot-like structures throughout the nucleus, and redistributes to a zone near the nuclear envelope in cells undergoing apoptosis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],
功能
function:Death-promoting transcriptional repressor.,sequence caution:Contaminating sequence. Potential poly-A sequence.,subunit:Interacts with Bcl-2 related proteins, EMD, with the adenovirus E1B 19 kDa protein and with DNA.,tissue specificity:Ubiquitous.,
蛋白名称
Bcl-2-associated transcription factor 1
其他名称
BCLAF1; BTF; KIAA0164; Bcl-2-associated transcription factor 1; Btf
细胞定位
Cytoplasm. Nucleus. Nucleus speckle . Nucleus, nucleoplasm .
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