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DFF45 (Cleaved-Thr225) rabbit pAb

说明书

BYab-00039

  • 20UL ¥460 50UL ¥945 100UL ¥1350
  • 货期: 3天左右

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宿主
反应性
应用
WB; ELISA
分子量(DA)
12 36kD
免疫原
Synthesized peptide derived from human DFF45 (Cleaved-Thr225)
特异性
This antibody detects endogenous levels of Human DFF45 (Cleaved-Thr225, protein was cleaved amino acid sequence between 224-225 )
来源
Polyclonal, Rabbit,IgG
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
WB 1:1000-2000 ELISA 1:5000-20000
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
浓度
1 mg/ml
背景(Background)
function:Inhibitor of the caspase-activated DNase (DFF40).,PTM:Caspase-3 cleaves DFF45 at 2 sites to generate an active factor.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Contains 1 CIDE-N domain.,subunit:Heterodimer of DFFA and DFFB.,
功能
DNA catabolic process, endonucleolytic, DNA metabolic process, DNA catabolic process, DNA fragmentation involved in apoptosis, apoptosis, induction of apoptosis, cell structure disassembly during apoptosis, nucleus organization,intracellular signaling cascade, cell death, macromolecule catabolic process, regulation of cell death, positive regulation of cell death, programmed cell death, induction of programmed cell death, death, cellular component disassembly,apoptotic nuclear changes, regulation of apoptosis, positive regulation of apoptosis, negative regulation of apoptosis,regulation of programmed cell death, positive regulation of programmed cell death, negative regulation of programmed cell death, cellular macromolecule catabolic process, negative regulation of cell death,
基因名称(Gene Name)
DFFA DFF1 DFF45 H13
蛋白名称
DFF45 (Cleaved-Thr225)
简称
DFF45
其他名称
DNA fragmentation factor subunit alpha (DNA fragmentation factor 45 kDa subunit;DFF-45;Inhibitor of CAD;ICAD)
Fields
>>Apoptosis
人基因ID
1676
人蛋白质序列数据库
O00273
小鼠基因ID
13347
小鼠蛋白质序列数据库
O54786
大鼠基因ID
大鼠蛋白质序列数据库
细胞定位
Cytoplasm.
组织表达
储存(Storage)
-20°C/1 year

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DFF45 (Cleaved-Thr225) rabbit pAb

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