免疫原
The antiserum was produced against synthesized peptide derived from human ALDH3B1. AA range:51-100
特异性
ALDH3B1 Polyclonal Antibody detects endogenous levels of ALDH3B1 protein.
来源
Polyclonal, Rabbit,IgG
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
WB: 1/500 - 1/2000. IHC: 1/100 - 1/300. ELISA: 1/40000.. IF 1:50-200
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
背景(Background)
This gene encodes a member of the aldehyde dehydrogenase protein family. Aldehyde dehydrogenases are a family of isozymes that may play a major role in the detoxification of aldehydes generated by alcohol metabolism and lipid peroxidation. The encoded protein is able to oxidize long-chain fatty aldehydes in vitro, and may play a role in protection from oxidative stress. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2014],
功能
catalytic activity:An aldehyde + NAD(P)(+) + H(2)O = an acid + NAD(P)H.,pathway:Alcohol metabolism; ethanol degradation; acetate from ethanol: step 2/2.,similarity:Belongs to the aldehyde dehydrogenase family.,tissue specificity:Highest expression in kidney and lung.,
蛋白名称
Aldehyde dehydrogenase family 3 member B1
其他名称
ALDH3B1; ALDH7; Aldehyde dehydrogenase family 3 member B1; Aldehyde dehydrogenase 7
Fields
>>Glycolysis / Gluconeogenesis;>>Histidine metabolism;>>Tyrosine metabolism;>>Phenylalanine metabolism;>>beta-Alanine metabolism;>>Metabolism of xenobiotics by cytochrome P450;>>Drug metabolism - cytochrome P450;>>Metabolic pathways
细胞定位
Cell membrane ; Lipid-anchor . Primarily in the plasma membrane as well as in some punctate structures in the cytoplasm.
组织表达
Highest expression in kidney and lung.