免疫原
Synthesized peptide derived from human FGD5
特异性
This antibody detects endogenous levels of FGD5 at Human, Mouse
组成（Formulation）
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺（Immunogen）
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
功能
Activates CDC42, a member of the Ras-like family of Rho- and Rac proteins, by exchanging bound GDP for free GTP. Mediates VEGF-induced CDC42 activation. May regulate proangiogenic action of VEGF in vascular endothelial cells, including network formation, directional movement and proliferation. May play a role in regulating the actin cytoskeleton and cell shape.
基因名称（Gene Name）
FGD5 ZFYVE23
蛋白名称
FYVE, RhoGEF and PH domain-containing protein 5 (Zinc finger FYVE domain-containing protein 23)
细胞定位
Cytoplasm, cytoskeleton . Cell projection, ruffle membrane . Endoplasmic reticulum . Golgi apparatus . Early endosome . In peripheral membrane ruffles, colocolizes with F-actin. In confluent HUVECs, detected at cell-cell-contact sites where it colocalizes with vascular endothelial cadherin/CDH5.
组织表达
Expressed in endothelial cells (at protein level).
储存（Storage）
-15°C to -25°C/1 year(Do not lower than -25°C)
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