免疫原
Synthesized peptide derived from human MAGI1
特异性
This antibody detects endogenous levels of MAGI1 at Human, Mouse,Rat
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺(Immunogen)
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
功能
May play a role as scaffolding protein at cell-cell junctions. May regulate acid-induced ASIC3 currents by modulating its expression at the cell surface (By similarity).
基因名称(Gene Name)
MAGI1 AIP3 BAIAP1 BAP1 TNRC19
蛋白名称
Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 (Atrophin-1-interacting protein 3) (AIP-3) (BAI1-associated protein 1) (BAP-1) (Membrane-associated guanylate kinase invert
细胞定位
Cell junction, tight junction . Cell membrane ; Peripheral membrane protein . Localizes to epithelial cells tight junctions.
组织表达
Widely expressed with the exception of skeletal muscle. Isoform 1, isoform 2 and isoform 6 are highly expressed in colon, kidney, lung, liver, and pancreas. Isoform 5 is predominantly expressed in brain and heart. Isoform 3 and isoform 4 are highly expressed in pancreas and brain.
储存(Storage)
-15°C to -25°C/1 year(Do not lower than -25°C)