免疫原
Synthesized peptide derived from human ATL3
特异性
This antibody detects endogenous levels of ATL3 at Human, Mouse,Rat
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺(Immunogen)
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
功能
GTPase tethering membranes through formation of trans-homooligomers and mediating homotypic fusion of endoplasmic reticulum membranes. Functions in endoplasmic reticulum tubular network biogenesis .
蛋白名称
Atlastin-3 (EC 3.6.5.-)
细胞定位
Endoplasmic reticulum membrane ; Multi-pass membrane protein . Localizes to endoplasmic reticulum tubules and accumulates in punctuate structures corresponding to 3-way junctions, which represent crossing-points at which the tubules build a polygonal network. .
组织表达
Expressed in the central nervous system and in dorsal root ganglia neurons. Expressed in peripheral tissues (at protein level).
储存(Storage)
-15°C to -25°C/1 year(Do not lower than -25°C)