免疫原
Synthesized peptide derived from human CERK
特异性
This antibody detects endogenous levels of CERK at Human, Mouse
组成（Formulation）
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺（Immunogen）
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
功能
Catalyzes specifically the phosphorylation of ceramide to form ceramide 1-phosphate . Acts efficiently on natural and analog ceramides (C6, C8, C16 ceramides, and C8-dihydroceramide), to a lesser extent on C2-ceramide and C6-dihydroceramide, but not on other lipids, such as various sphingosines . Shows a greater preference for D-erythro isomer of ceramides . Binds phosphoinositides .
基因名称（Gene Name）
CERK KIAA1646
蛋白名称
Ceramide kinase (hCERK) (EC 2.7.1.138) (Acylsphingosine kinase) (Lipid kinase 4) (LK4)
细胞定位
Cytoplasm . Cell membrane ; Peripheral membrane protein .
组织表达
High level expression in heart, brain, skeletal muscle, kidney and liver; moderate in peripheral blood leukocytes and thymus; very low in spleen, small intestine, placenta and lung.
储存（Storage）
-15°C to -25°C/1 year(Do not lower than -25°C)
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