免疫原
Synthesized peptide derived from human VAMP2
特异性
This antibody detects endogenous levels of VAMP2 at Human, Mouse,Rat
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺(Immunogen)
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
功能
Involved in the targeting and/or fusion of transport vesicles to their target membrane (By similarity). Major SNARE protein of synaptic vesicles which mediates fusion of synaptic vesicles to release neurotransmitters. Essential for fast vesicular exocytosis and activity-dependent neurotransmitter release as well as fast endocytosis that mediates rapid reuse of synaptic vesicles (By similarity) . Modulates the gating characteristics of the delayed rectifier voltage-dependent potassium channel KCNB1.
基因名称(Gene Name)
VAMP2 SYB2
蛋白名称
Vesicle-associated membrane protein 2 (VAMP-2) (Synaptobrevin-2)
细胞定位
Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane ; Single-pass type IV membrane protein . Cell membrane . Colocalizes with PRKCZ and WDFY2 in intracellular vesicles (PubMed:17313651). .
组织表达
Nervous system and skeletal muscle.
储存(Storage)
-15°C to -25°C/1 year(Do not lower than -25°C)