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PDE4A mouse mAb

BYmab-18210

  • 20UL ¥460 50UL ¥945 100UL ¥1350
  • 货期: 3个工作日

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宿主
反应性
应用
WB
分子量(DA)
97kD
免疫原
Synthesized peptide derived from human PDE4A AA range:530-580
特异性
This antibody detects endogenous levels of PDE4A at Human, Mouse,Rat
来源
Monoclonal, Mouse,IgG
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
WB 1:500-2000
纯化工艺(Immunogen)
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
浓度
1 mg/ml
背景(Background)
功能
Hydrolyzes the second messenger 3',5'-cyclic AMP (cAMP), which is a key regulator of many important physiological processes. ; [Isoform 1]: Efficiently hydrolyzes cAMP. ; [Isoform 2]: Efficiently hydrolyzes cAMP. ; [Isoform 3]: Efficiently hydrolyzes cAMP. The phosphodiesterase activity is not affected by calcium, calmodulin or cyclic GMP (cGMP) levels. Does not hydrolyze cGMP. ; [Isoform 4]: Efficiently hydrolyzes cAMP. ; [Isoform 6]: Efficiently hydrolyzes cAMP. ; [Isoform 7]: Efficiently hydrolyzes cAMP.
基因名称(Gene Name)
PDE4A DPDE2
蛋白名称
cAMP-specific 3',5'-cyclic phosphodiesterase 4A (EC 3.1.4.17) (DPDE2) (PDE46)
简称
其他名称
Fields
人基因ID
人蛋白质序列数据库
小鼠基因ID
小鼠蛋白质序列数据库
大鼠基因ID
大鼠蛋白质序列数据库
细胞定位
[Isoform 1]: Cytoplasm, perinuclear region .; [Isoform 2]: Cytoplasm, perinuclear region . Cell projection, ruffle membrane .; [Isoform 3]: Cytoplasm, cytosol .; [Isoform 4]: Membrane; Peripheral membrane protein . Isoform 4 has propensity for association with membranes. .; [Isoform 6]: Cytoplasm, perinuclear region .; [Isoform 7]: Cytoplasm, cytosol. Membrane; Peripheral membrane protein . Predominantly cytosolic. .
组织表达
[Isoform 1]: Expressed in lymphoid cell subsets including CD8-positive T cells and T-helper 2 cells. Expressed in dendritic cells. ; [Isoform 2]: Highly expressed in liver, stomach, testis, thyroid and adrenal glands and at a lower extent in placenta, kidney, pancreas, ovary, uterus and skin. Expressed in myeloid cell subsets including dendritic cells, monocytes, macrophages, eosino
储存(Storage)
-15°C to -25°C/1 year(Do not lower than -25°C)

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PDE4A mouse mAb

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