免疫原
Synthesized peptide derived from human ATPB
特异性
This antibody detects endogenous levels of ATPB at Human, Mouse,Rat
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺(Immunogen)
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
功能
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Subunits alpha and beta form the catalytic core in F(1). Rotation of the central stalk against the surrounding alpha(3)beta(3) subunits leads to hydrolysis of ATP in three separate catalytic sites on the beta subunits.
基因名称(Gene Name)
ATP5B ATPMB ATPSB
蛋白名称
ATP synthase subunit beta, mitochondrial (EC 3.6.3.14)
细胞定位
Mitochondrion inner membrane ; Peripheral membrane protein ; Matrix side .
储存(Storage)
-15°C to -25°C/1 year(Do not lower than -25°C)